For many centuries, fenugreek has been one of the most popular spices and vegetables serving as an integral part of culinary practices across many cultures. Fenugreek contains exceptional nutritional and medicinal properties, but scientific evidence for its potential health benefits has been considerably understudied and is beginning to grow. This book is a comprehensive compilation and documentation on the scientific profile of fenugreek and its phytoconstituents, including their most known applications and health benefits. It features a wide range of chapters written by highly experienced academics and industrial professionals. Topics cover applications of fenugreek including information on nutrition, fitness supplements, functional food, and excipients of novel drug delivery systems. In addition, it features topics on related products in the areas of nutraceuticals, functional food preparations, and complementary medicines. Features: * Comprehensive review of traditional wisdom and modern scientific evidence on fenugreek * Presents scientific evidence of fenugreek as an ingredient for product development formulation * Contains information on extraction methods, risk assessment, claim validations, and the regulatory status of fenugreek-based products * Covers broad physiological benefits of fenugreek in management of diabetes mellitus, primary hyperlipidemia, inflammation and pain, neuropathy and neuroinflammation, neurological and psychological disorders, kidney and lung disorders, as well as immunological, infectious, and malignant disorders * Enhances awareness of existing scientific knowledge surrounding fenugreek, whilst encouraging future scientific research towards better and safer nutritional and medicinal applications This book is a valuable resource of information on fenugreek for researchers, students, nutritionists, sport medicine practitioners, fitness enthusiasts and trainers, naturopaths, traditional practitioners, and toxicologists. This book helps industries in the fields of nutraceuticals, fitness and sports medicine products to develop their future products. However, this book is not a substitute for medical advice or recommendations.

For many centuries, fenugreek has been one of the most popular spices and vegetables serving as an integral part of culinary practices across many cultures. Fenugreek contains exceptional nutritional and medicinal properties, but scientific evidence for its potential health benefits has been considerably understudied and is beginning to grow. This book is a comprehensive compilation and documentation on the scientific profile of fenugreek and its phytoconstituents, including their most known applications and health benefits. It features a wide range of chapters written by highly experienced academics and industrial professionals. Topics cover applications of fenugreek including information on nutrition, fitness supplements, functional food, and excipients of novel drug delivery systems. In addition, it features topics on related products in the areas of nutraceuticals, functional food preparations, and complementary medicines. Features: * Comprehensive review of traditional wisdom and modern scientific evidence on fenugreek * Presents scientific evidence of fenugreek as an ingredient for product development formulation * Contains information on extraction methods, risk assessment, claim validations, and the regulatory status of fenugreek-based products * Covers broad physiological benefits of fenugreek in management of diabetes mellitus, primary hyperlipidemia, inflammation and pain, neuropathy and neuroinflammation, neurological and psychological disorders, kidney and lung disorders, as well as immunological, infectious, and malignant disorders * Enhances awareness of existing scientific knowledge surrounding fenugreek, whilst encouraging future scientific research towards better and safer nutritional and medicinal applications This book is a valuable resource of information on fenugreek for researchers, students, nutritionists, sport medicine practitioners, fitness enthusiasts and trainers, naturopaths, traditional practitioners, and toxicologists. This book helps industries in the fields of nutraceuticals, fitness and sports medicine products to develop their future products. However, this book is not a substitute for medical advice or recommendations.

Rheumatoid arthritis is progressive, autoimmune inflammatory chronic disorder which do not have curative treatment yet. Aryl and hetero-aryl acids has maximum share of anti-inflammatory drugs in the therapeutics today as non steroidal anti-inflammatory drugs (NSAIDs). Benzimidazole moiety with heteroaryl and psudoacedic nature is promising moiety for development of NSAIDs. In the present project, synthesis, pharmacological evaluation, probable mechanism of action and quantitative structure-activity relationship (QSAR) of benzmidazole-2-carboxylic acids are reported. The excellent efficacy and safety was observed for benzimidaxole-2-carboxylic acid derivatives in laboratory animal models of inflammation and rheumatoid arthritis without side-effect of gastrointestinal disturbances. The reliving effects against pain and fever in experimental animal models suggested promise as potential NSAID.